Tissue composite graft lacking sinuses may well prone to develop endocarditis post aortic root replacement: An untested hypothesis

Maqsood M. Elahi, Dennis Ho, Kenton J. Zehr


A 72 year-old female with acute prosthetic aortic root endocarditis and systolic congestive heart failure underwent a homograft revision within 6-months. Initially she underwent root replacement with a straight composite graft for a severely stenotic aortic valve and root dilatation. Over a 6-month period, she developed a progressively audible holosystolic murmur. Echocardiography demonstrated a vibrating stuttering of the prosthetic valve cusps on M-mode. This was exaggerated with aortic root endocarditis vegetations on cusps. We hypothesize that this repetitive severe turbulent flow related to a Venturi effect damaged the straight tube graft-aortic root and prosthetic valve cusps in our case.

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DOI: https://doi.org/10.5430/jbgc.v3n3p49

Journal of Biomedical Graphics and Computing    ISSN 1925-4008 (Print)   ISSN 1925-4016 (Online)

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