Transient stress lymphocytosis uncovers the underlying B-cell lymphoproliferative disorder

Abstract

Transient stress lymphocytosis or stress induced lymphocytosis is a relative uncommon reactive process. It typically associates with emergency medical conditions, such as cardiac stress, sickle crises, abdominal pain, and trauma. Immunophenotypic analysis of stress induced lymphocytosis or transient stress lymphocytosis reveals an increase in absolute numbers of T, B, and natural killer cells with a normal immunophenotype. A clonal process has never been reported. Here we report a case of transient stress lymphocytosis revealing the underlying lymphoproliferative disorder.