Solid tumors and photobiomodulation: A novel approach to induce physiologically reparative homeostasis / homeokinesis-review

Abstract

It has been argued that loss of homeostasis is what, in essence, allows cancer cells to divide and invade tissues. Hence, novel anticancer therapies should aim not only at killing cancer cells, but at reestablishing homeostasis /homeokinesis. This review aims to present and discuss evidence on the potential use of laser photobiomodulation in the treatment of solid tumors. We propose that, by supplying external electromagnetic (light) energy within parameters capable of powering and regulating electrochemical biological systems, photobiomodulation may help restore homeostasis/homeokinesis–inducing physiologically reparative effects for disease reversal in cancer and other complex diseases. This view is based on more than two decades of research, which indicates that light can modulate physiologic energy pathways and, in particular, ATP generation and signaling via the “classic” respiratory chain pathway and through light-water interactions in tissues and oxygen-independent mechanisms.