The role of 18F-FDG-PET/CT in initial staging and re-staging of head and neck cancer

Abdullah Demirkan, Pelin Ozcan Kara, Kayhan Oztürk, Oktay Sari, Nazim Barıs Kanat, Izzet Ozgür Ozlük, Ahmet Kibar

Abstract


The aim of this study is to have a solid basis for the effectiveness of the 18F-FDG-PET/CT imaging technique, which hasknown advantages for patients with head and neck cancers during staging and restaging prior to treatment and to comparethis method with the corresponding clinical and radiological methods.

A total of 139 patients with squamous cell head and neck carcinoma underwent PET/CT imaging. A total of 146 PET/CTimaging was performed in all patients. PET/CT imaging performed for staging and restaging in 36 and 103 patients,respectively. At least one conventional imaging (CI) as CT and/or MRI was performed for each one of the total patients.PET/CT studies revealed 66 true positive, 72 true negative, 4 false positive and 4 false negative results whereas the samevalues for CI were 65, 64, 4 and 6, respectively.

When all studies were analyzed on the basis of lesion for PET/CT, specificity was 94.7%, and sensitivity being 94.2%,where as corresponding values for conventional imaging methods were found 94.1% and 91.5% respectively. Recurrentlesions have been detected with PET/CT and treatment management was changed in 29 of 139 patients.FDG-PET/CT improves the diagnostic accuracy in head and neck cancer patients.


Full Text: PDF DOI: 10.5430/jbgc.v4n3p57

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Journal of Biomedical Graphics and Computing
ISSN 1925-4008 (Print)   ISSN 1925-4016 (Online)
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