Burkitt lymphoma with additional isochromosome 1q in an adult HIV-positive patient

Raja Zahratul Azma Raja Sabudin, Suziana M Nor, Azlin Ithnin, Hafiza Alauddin, Rafeah Tumian, Chia Wai Kit, Salwati Shuib

Abstract


Burkitt’s lymphoma (BL) continues to pose challenges in the human immunodeficiency virus (HIV)-infected population and may present at more advance stages with multiple areas of extranodal involvement. Other chromosomal abnormality in addition to the characteristic t (8:14) translocation also associated with poor outcome in BL. Here we report a case of an HIV seropositive adult male with the diagnosis of BL who presented with bone marrow and peripheral blood involvement of the disease. Cytogenetic analysis showed presence of complex chromosomal abnormality, with characteristic translocation of t (8:14) and an additional isochromosome 1q.

 


Full Text: PDF DOI: 10.5430/crcp.v1n2p5

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Case Reports in Clinical Pathology

ISSN 2331-2726 (Print)  ISSN 2331-2734(Online)

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